Dr. Lofton is a Clinical Associate Professor of Medicine and Surgery at NYU Langone Health, where she has served as director of the Medical Weight Management Program at NYU Langone Health Weight Management Program since 2012. Here, she designed the popular New You weight loss program to help her patients obtain results while fostering nutrition education and placing emphasis on a healthy lifestyle. She is currently involved in clinical research pertaining to the pharmacotherapy to treat weight regain after bariatric surgery as well as clinical drug trials. In her faculty role, Dr. Lofton continues to educate students and other physicians about diagnosing and treating obesity. She also educates the general public about the importance of maintaining a healthy weight through lectures, workshops, written, audio, and video media. She has served on the board of the Obesity Action Coalition and on the Bariatric Medicine committee for the American Society for Metabolic and Bariatric Surgery. In 2016, she became a founding member of the NYU Comprehensive Program on Obesity as well as being appointed Program Director of the Clinical Obesity Medicine Fellowship.